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04/21/2025
Tightness in your chest and shortness of breath are just some of the classic symptoms of respiratory illnesses. Asthma is one such disease that has claimed the lives of about 455,550 people in 2019, and COPD is another that has caused an estimated 3.5 million deaths in the year 2021. Asthma and COPD can be debilitating conditions that end up significantly affecting your quality of life. If you are a person who is going through asthma or COPD, or if you have a loved one going through this condition, it is important to know a few details about these diseases. In this blog, we will be learning about the causes and ways to manage the diseases mentioned above. We will also be brushing through a condition known as ACOS. All these conditions might seem scary, but modern medicine possesses all the tools to manage symptoms efficiently. However, there hasn't yet been an established cure for these conditions. One such controller medicine is the Levalbuterol and Budesonide Respules. Keep reading to find out more about this.
Levalbuterol and Budesonide Respules are present in the following doses of each of the drugs: Levalbuterol (1.25 mg) + Budesonide (0.5 mg) in Respules of 2mL. This medication is administered through a nebulizer and is used as a controller medication for conditions such as asthma and COPD. The budesonide present in this medication is a corticosteroid that acts as an anti-inflammatory agent, while Levalbuterol is a beta-2 adrenergic receptor that is used to relax the smooth muscles around the respiratory tract. Together, these medications induce a relaxing effect on the respiratory tract that manages the constriction and inflammation that occurs in asthma and COPD.
This medicine usually does not have any severe side effects as inhalation of the medicine eliminates the long pathway of absorption and has maximum efficiency at the targeted sites. However, you need to watch out for a few common side effects that may occur along with the use of this medication.
Oral thrush (fungal infection in the mouth)
Headache
Sore throat or a harsh voice
Back pain
Fast heartbeat
Muscle cramps or tremors
Most of these side effects resolve by themselves once you adjust to the medication; however, if you feel that they are troublesome, you can talk to your doctor about them. To prevent oral thrush, it is recommended that you should rinse your mouth thoroughly after every use.
If you happen to develop a severe allergic reaction to this medication, you should seek medical attention immediately. You may experience symptoms such as hives, itching, wheezing, etc., before it turns into anaphylaxis. If you suspect that you may be allergic to this medication, ensure that you have an EpiPen nearby while inhaling this medication.
Here are some strict guidelines you should follow before or while using this medication to receive the maximum benefit of this medication without any unnecessary side effects.
This medication is not recommended for children under the age of 6 as its safety has not yet been established in this age group.
Do not drink grapefruit juice or have any form of grapefruit while taking this medication, as it may lead to unnecessary and adverse effects.
As your immune system might weaken with the intake of this medication, you should avoid crowded places and contact with people who may have a contagious disease/ have gotten a live vaccination recently.
Please inform your doctor if you have any of the following existing conditions, as it can severely impact the risks you face while taking this medication.
Lapp-lactase deficiency
High blood pressure
Malabsorption or intolerance of galactose and glucose
Diabetes
Hypoalkemia
Glaucoma or cataracts
Chickenpox, measles, tuberculosis
Asthma and COPD are diseases that affect an individual's respiratory tract. This includes spasms and contracts of the trachea, rigidity of alveoli, and inflammation in the breathing tract. Oftentimes, one might find it hard to breathe, and also coughing, wheezing, mucus, and other symptoms that come as byproducts of these diseases.
Levalbuterol helps rest the muscles around the respiratory tract, which opens up the airways. Levalbuterol also plays an immunosuppressive role by inhibiting the white blood cells from acting upon the airway (a chief cause of asthma).
Budesonide is a corticosteroid that acts by decreasing vasodilation, thereby reducing the inflammation that may have been previously present in the respiratory tract. This mediation can provide relief for up to several days.
Managing chronic conditions such as asthma and COPD requires consistent habits and other approaches that will focus not only on your respiratory health but also your overall health.
It is important to take all your prescribed medication and not to shy away from any daily controller medications. It is also not a good idea to rely on only rescue medications if you have been prescribed a controlled medication. Your doctor has prescribed it to you only when the benefits of the medicine outweigh the risks it might cause (rarely). You should not skip any doses of your medication as it will lead you to live a better quality of life.
Eating a healthy diet, regularly exercising with moderate level activity, and having good stress management techniques can significantly reduce the toll asthma attacks take on your body. Asthma does not only harm the respiratory system but even the cardiovascular system and nervous system, spiking adrenaline and cortisol levels regularly. This elevated stress needs to be managed efficiently.
Regular check-ups with your family physician and avoiding triggers for your asthma/ COPD attacks can be the first step towards managing these diseases in the long term. You can also practice breathing techniques to better your oxygen intake, as that can sometimes be an issue for people who have constant shortness of breath. It is also important to be up to date with all the seasonal vaccines, as any upper respiratory illness can become serious if you have asthma or COPD.
Yes, this is a condition known as ACOS or Asthma-COPD Overlap Syndrome, where one can have both conditions simultaneously. It is usually not self-diagnosable and requires a medical professional to diagnose this disease. The pathophysiology and management of this disease can be pretty tricky.
This disease may occur in about 10% to 40% of patients who have COPD and 15% to 35% of patients who have asthma. The main difference between having one of these illnesses and having both of them is that people with ACO or ACOS can suffer from an increased number of exacerbations and require more frequent hospital visits for their condition.
The symptoms of this disease are usually similar to those of COPD and asthma. They include difficulty breathing, excess mucus secretions, tiredness, coughing, shortness of breath and wheezing. There is no defining symptom of this disease. Therefore, doctors conduct thorough tests to diagnose this disease.
Managing the symptoms of asthma and COPD can feel like a full-time job. There are many ways to manage these illnesses, but a healthy mix of lifestyle choices and medications provides the best results. There are also structured programs known as pulmonary rehabilitation that can help you improve the functioning of your lungs and better train you to live with the complications that are caused by these diseases. Your disease does not need to dictate your life.
Levalbuterol and Budesonide Respules are used by inhaling through a nebulizer to control and manage symptoms of COPD and asthma. This medication will lower the overall wheezing, shortness of breath, and inflammation caused by the disease. However, this is not a rescue medication.
The budesonide present in this medication is a corticosteroid that acts as an anti-inflammatory agent, while Levalbuterol is a beta-2 adrenergic receptor that is used to relax the smooth muscles around the respiratory tract.
One of the most common side effects of this medication is an oral thrush, which is a fungal infection that occurs on your tongue and around your buccal cavity. You can rinse your buccal cavity thoroughly with water after administration of this medication to reduce the chances of developing a thrush.
Other side effects may include a sore throat, flu-like symptoms, headache, back pain, or a fast heartbeat.
This medication should be used exactly as prescribed to you by your doctor. Here are a few ways to make sure you receive the correct dosage of this medication.
Keep your mouth firmly attached to the mouthpiece so that all the medicine can be sent to your lungs. Do not leave any gaps in your mask or mouthpiece.
Keep breathing through the mouthpiece or the mask (whichever you are using) for about 5-20 minutes or till all the medicine is used up in the container.
This medication is not recommended for children under the age of 6. It can be used safely in older adults. However, it is important to practice caution while administering any medication to older patients as they are the most likely to need a dose adjustment.
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