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04/17/2025
Depression is not just a feeling but much more than that, and you are not alone in this battle. With 3 out of 10 people going through this condition, what is more staggering is how most of them are unaware of their diagnosis. They seem to be battling this alone and afraid. It’s a medical condition that causes disturbances in sleep; it may also lead to unhappiness, tiredness, and loss of interest in activities; it can make you feel worthless and much more. Major depressive disorder negatively affects feelings, creates thoughts of self-harm, and negative changes in behavior. Fortunately, it is treatable due to medical advancements, which led to newer yet effective antidepressants. One of which is a generic Valdoxan 25MG tablet that contains Agomelatine, which is the key active ingredient that is responsible for managing mood disorders. If you are looking for options on how to manage mood disorders, you are at the right place. Here, we are going to break down everything you need to know about Valdoxan 25mg.
Valdoxan 25 mg is for depression and features Agomelatine as its powerful active ingredient, which is an atypical antidepressant. This antidepressant acts as an agonist for melatonin receptors (MT1 and MT2). This means that it replicates melatonin’s activity in the brain, helping improve the quality of sleep and overall well-being, which helps fight against depression. It also acts as an antagonist for serotonin (5-HT2C) receptors, which increases neurotransmitters such as dopamine and norepinephrine levels in the brain. This mechanism of action reduces the levels of depression with minimum side effects. This effective dual action takes care of both mood and quality sleep, which is directly linked with depression. This gives an added advantage to Valdoxan over other antidepressants available on the market. You can find cheap Valdoxan 25mg (generic) at online pharmacies with the same efficacy and effectiveness at an affordable price.
You should buy Valdoxan 25mg only if your doctor has prescribed it and take it exactly as your healthcare provider has told you to. In case of any confusion, you should consult your doctor or pharmacist again. The recommended dose is one tablet of Valdoxan 25mg before bed; however, in very few cases, doctors may prescribe two tablets (50 mg) that must be taken together before bedtime. Two tablets (50 mg) is the maximum recommended dosage that should not be exceeded in a day.
The prescribed dosage should be completed without fail, even if you feel you have no symptoms now. Recent experiences with treating depression or anxiety with Valdoxan 25mg indicate that the treatment should be undergone for at least 6 months for better recovery. You can take Valdoxan with or without food.
Like all other medications, Valdoxan may cause some side effects. However, not everyone has to experience those side effects. Below are the common side effects of Valdoxan.
Dizziness or headache
Nausea or digestive discomfort
Fatigue
Vivid dreams or mild anxiety
In case you encounter serious side effects like darkening of the urine, light-colored stool, yellowish skin or eyes, pain in the upper right side of the belly, and unusual fatigue. You need to immediately consult your doctor and seek medical help by contacting the emergency helpline number, calling an ambulance, or rushing to the emergency room. Please consult your doctor for the prescription if any alternative medication needs to be taken.
Any antidepressant comes with strict precautionary guidelines, which, if not kept in mind, may lead to serious health risks. Below are some of the standard safety measures you should always keep in mind if you are taking Agomelatine:
Valdoxan 25mg tablet is not recommended in pre or ongoing pregnancy and to breastfeeding women unless it is absolutely necessary; in case the need arises, you must always consult your doctor before taking Valdoxan 25mg as if ignored, there is a potential risk to fetal development, the drug can be transmitted through the breast milk to the new-born which may have a long-term effect on the baby.
Driving, using machines, and alcohol consumption are not recommended after taking the Valdoxan Tablet 25mg because the medication may cause drowsiness, which may lead to serious consequences, and due to alcohol consumption, liver toxicity may increase.
Patients with severe or mild kidney or liver impairments should consult their doctor before taking the Valdoxan 25mg tablet as if ignored, it may lead to serious consequences like liver damage, Jaundice, Hepatitis, and, in a few cases, liver failure.
Do not take Valdoxan 25MG tablet if you are allergic to Agomelatine, as it may cause mild to severe skin rashes like anaphylaxis.
Valdoxan 25mg tablets are not recommended for patients under 18 years or above 75 years of age as these age groups are at higher risk of side effects. Please get in touch with your doctor before taking the medication.
Depression is a state of mental condition that leads to persistent feelings of loneliness, emptiness, sadness, and hopelessness. It can even change your thoughts, the way you look at things, your sleep cycle, and your eating habits, and you can notice a change in your behavior. The type of depression may differ from person to person as per the situation/condition, which is fortunately curable through various therapies/talk therapies, medications, or sometimes both are needed. As soon as the symptoms are recognized, one should immediately seek medical help.
Biologically, it is stated that depression is a state of chemical imbalance; however, the complexity of the situation cannot be described with this figure of speech as there may be many other causes of depression, including stressful events of life, genetic vulnerability, or the faulty regulation of mood by the brain and many more. Depression can also result from medication side effects or chronic medical conditions, such as diabetes. Scientists have researched a lot about the causes of depression; however, this research is far away from complete, as the same symptoms of depression can be caused by different reasons or vice versa.
Having physical effects or symptoms is very common in depression. Vague aches and pain are usual symptoms of depression. The symptoms like joint pain, chronic back pain, gastrointestinal issues, disturbed sleep cycle, psychomotor disturbances, and appetite changes are some of the examples of physical effects of depression on a body. Physical pain and depression are biologically interconnected to what’s happening in the brain beyond cause and effect as they are not just coincidences or imagined sensations; neurotransmitters like serotonin and norepinephrine are very powerful brain chemicals that not only regulate the mood but also how the body recognizes pain. Suppose the levels are disrupted, as happens in most cases of depression. In that case, the brain may get confused even by the harmless body signals as pain or may restrict our body’s natural pain-killing chemicals released by your brain to calm your pain.
Usually, depression can be treated by Psychotherapy, which is the initial step in any depression case that includes talk therapy or speaking with a therapist; however, in some cases, medical treatments like Selective serotonin reuptake inhibitors (SSRIs) are also combined with antidepressants to treat moderate and severe depression.
Among all the mental disorders, depression is the most treatable disorder, as 70% to 90% of people suffering from depression respond well to its treatment. The early signs of depression can be managed efficiently by one form of treatment, which is talk therapy or speaking with psychotherapists; however, in a few cases, a combination of treatments works best.
Depression can be a short-term or a long-term issue, and treatment does not always cure your depression completely. However, it is seen that it makes your depression and its symptoms more manageable. The use of the right combination of medications and therapies can manage the symptoms. You should always contact your healthcare provider if you feel that the treatment is doing no good to your mental and physical health. They are the only ones who can help you try different treatment plans that may be more helpful in treating your condition. However, a strong support system and a connected community play crucial roles in healing and recovery, providing emotional support and encouragement in the treatment and helping reduce feelings of loneliness. Eventually, being a part of a connected community, like cultural organizations or online platforms, can reduce the feelings of unhappiness in your life. Sharing your views and experiences with community members helps you feel that you are not alone in this battle and gives you hope that you will be back to normal soon.
Valdoxan 25mg consists of Agomelatine as its active ingredient, which is an atypical antidepressant that acts as a melatonin receptor agonist. Additionally, it works as an antagonist at serotine (5-HT2C) receptors, spiking dopamine and norepinephrine levels in the frontal cortex of the brain. Therefore, its unique dual action takes care of both mood and sleep cycle, which is directly associated with depression.
Valdoxan 25mg acts as a melatonin receptor agonist that resynchronizes the sleep cycle and also acts as a 5-HT2C receptor antagonist, which blocks these receptors, due to which dopamine and norepinephrine levels increase in the brain. This unique dual action offers a distinct advantage over other antidepressants available on the market.
Some of the most common and mild side effects of this medication are:
Headache
Dizziness
Nausea
Fatigue
Abdominal discomfort
Vivid dreams or nightmares
Studies suggest that it may take two to four weeks for Valdoxan 25 mg to show results if taken on time and as prescribed. For long-term recovery, the treatment should continue for at least six months or longer, as advised by your healthcare provider.
You should not take VALDOXAN 25mg together with any other medicine that is used in the treatment of depression, like fluvoxamine or ciprofloxacin (an antibiotic). Please inform your doctor in advance if you have any other medication ongoing.
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